| Gene Information | |
|---|---|
| Gene Name | ARTN |
| Organism | Homo sapiens (Human) |
| Gene Length | 220 |
| Protein Names | Artemin (Enovin) (Neublastin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000117407 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q5T4W7 |
| Gene Card | ARTN |
| Uniprot ID | Q5T4W7 |
| Pfam | PF00019 |
| In ASD | no |
| Allosteric Prediction | no (-0.524295046) |
| Ortholog in Animals | Alpaca_ ARTN ( ortholog_one2one ) GuineaPig_ ARTN ( ortholog_one2one ) Macaque_ ARTN ( ortholog_one2one ) Mouse_ Artn ( ortholog_one2one ) Pig_ ARTN ( ortholog_one2one ) Rat_ Artn ( ortholog_one2one ) Rabbit_ ARTN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PSPN, GDNF, NRTN |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain. {ECO:0000269|PubMed:10583383, ECO:0000269|PubMed:9883723}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.010990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2ASK (X-ray 1.55A ) 2GH0 (X-ray 1.92A ) 2GYR (X-ray 2.60A ) 2GYZ (X-ray 1.76A ) 6Q2S (EM 3.80A ) |
| DBSNP | rs2242637 |
| Subcellular location [CC] | Secreted {ECO:0000250}. |
| Mouse PG classification | NA |
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