Gene Information
Gene NameTFAP2E
OrganismHomo sapiens (Human)
Gene Length442
Protein NamesTranscription factor AP-2-epsilon (AP2-epsilon) (Activating enhancer-binding protein 2-epsilon)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000116819 )
Evolutionary StageEumetazoa
AlphaFoldDBQ6VUC0
Gene CardTFAP2E
Uniprot IDQ6VUC0
PfamPF03299
In ASDno
Allosteric Predictionno (-1.347104926)
Ortholog in AnimalsAlpaca_ TFAP2E ( ortholog_one2one )
Dog_ TFAP2E ( ortholog_one2one )
GuineaPig_ TFAP2E ( ortholog_one2one )
Macaque_ TFAP2E ( ortholog_one2one )
Mouse_ Tfap2e ( ortholog_one2one )
Pig_ TFAP2E ( ortholog_one2one )
Rat_ Tfap2e ( ortholog_one2one )
Rabbit_ TFAP2E ( ortholog_one2one )
OhnologsTFAP2B, TFAP2D, TFAP2C, TFAP2A
ParalogsTFAP2B, TFAP2A, TFAP2C, TFAP2D
TissueNA
Tissue SpecificityExpressed in skin, primary keratinocytes, immortalized keratinocytes, and HeLa cell line. {ECO:0000269|PubMed:14636996}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000250|UniProtKB:Q6VUP9}.
Mouse PG classificationNA
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