| Gene Information | |
|---|---|
| Gene Name | N4BP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 896 |
| Protein Names | NEDD4-binding protein 1 (N4BP1) (EC 3.1.-.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000102921 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O75113 |
| Gene Card | N4BP1 |
| Uniprot ID | O75113 |
| Pfam | PF11977 |
| In ASD | no |
| Allosteric Prediction | no (-1.001131082) |
| Ortholog in Animals | Alpaca_ N4BP1 ( ortholog_one2one ) Dog_ N4BP1 ( ortholog_one2one ) GuineaPig_ N4BP1 ( ortholog_one2one ) Macaque_ N4BP1 ( ortholog_one2one ) Mouse_ N4bp1 ( ortholog_one2one ) Pig_ N4BP1 ( ortholog_one2one ) Rat_ N4bp1 ( ortholog_one2one ) Rabbit_ N4BP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ZC3H12B, NYNRIN, ZC3H12C, ZC3H12D, ZC3H12A, KHNYN |
| Tissue | NA |
| Tissue Specificity | Detected in heart, lung, brain, liver, skeletal muscle, pancreas, kidney, spleen, testis and ovary. {ECO:0000269|PubMed:9734811}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6Q3V (X-ray 1.88A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q6A037}. Nucleus {ECO:0000250|UniProtKB:Q6A037}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q6A037}. Nucleus, PML body {ECO:0000250|UniProtKB:Q6A037}. Note=Primarily localizes to the nucleolus. Also localizes to the PML nuclear bodies, when desumoylated. {ECO:0000250|UniProtKB:Q6A037}. |
| Mouse PG classification | NA |
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