| Gene Information | |
|---|---|
| Gene Name | DUSP7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 419 |
| Protein Names | Dual specificity protein phosphatase 7 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PYST2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000164086 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q16829 |
| Gene Card | DUSP7 |
| Uniprot ID | Q16829 |
| Pfam | PF00782; PF00581 |
| In ASD | no |
| Allosteric Prediction | yes (0.182959857) |
| Ortholog in Animals | Alpaca_ DUSP7 ( ortholog_one2one ) GuineaPig_ DUSP7 ( ortholog_one2one ) Macaque_ DUSP7 ( ortholog_one2one ) Mouse_ Dusp7 ( ortholog_one2one ) Pig_ DUSP7 ( ortholog_one2one ) Rat_ Dusp7 ( ortholog_one2one ) |
| Ohnologs | DUSP9, DUSP6 |
| Paralogs | DUSP6, DUSP4, DUSP12, DUSP10, STYXL2, SSH3, DUSP19, DUSP1, KASH5, SSH1, DUSP29, DUSP16, DUSP21, DUSP2, DUSP8, DUSP13, EPM2A, DUSP26, STYX, SSH2, PTPMT1, DUSP22, DUSP18, DUSP15, DUSP14, DUSP28, STYXL1, DUSP5, DUSP9, DUSP3 |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in liver (PubMed:8670865). Expressed at significantly higher levels in malignant hematopoietic cells than in corresponding non-malignant cells (PubMed:14576828). {ECO:0000269|PubMed:14576828, ECO:0000269|PubMed:8670865}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.08(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 4Y2E (X-ray 1.67A ) |
| DBSNP | rs34821455 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:9788880}. |
| Mouse PG classification | NA |
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