| Gene Information | |
|---|---|
| Gene Name | ALK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 503 |
| Protein Names | Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P37023 |
| Gene Card | ACVRL1 |
| Uniprot ID | P37023 |
| Pfam | PF07714; PF08515 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);0.090584(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LCR (NMR - ) 3MY0 (X-ray 2.65A ) 4FAO (X-ray 3.36A ) 6SF1 (X-ray 2.80A ) 6SF2 (X-ray 3.30A ) 6SF3 (X-ray 2.30A ) 7PPC (X-ray 3.60A ) |
| DBSNP | rs149664056 rs1184716348 rs774389618 rs387906392 rs121909285 rs863223409 rs1131691346 rs1466116430 rs1480110873 rs863223414 rs1085307405 rs1330837892 rs1481094868 rs753792569 rs28936687 rs754283265 rs1565593639 rs762773076 rs1804508 rs387906393 rs1592223978 rs1085307410 rs1565594311 rs1565594410 rs863223413 rs1592224349 rs762287966 rs1592224412 rs28936688 rs1060503248 rs28936401 rs28936399 rs1555153277 rs959973779 rs1131691686 rs121909286 rs121909289 rs1565595129 rs121909284 rs121909284 rs121909287 rs141653630 rs1085307419 rs1565596498 rs1085307426 rs139142865 rs121909288 rs113700354 rs1085307428 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:26176610}; Single-pass type I membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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