| Gene Information | |
|---|---|
| Gene Name | ARP |
| Organism | Homo sapiens (Human) |
| Gene Length | 182 |
| Protein Names | Mesencephalic astrocyte-derived neurotrophic factor (Arginine-rich protein) (Protein ARMET) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P55145 |
| Gene Card | MANF |
| Uniprot ID | P55145 |
| Pfam | PF10208; PF20145 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KVD (NMR - ) 2KVE (NMR - ) 2W51 (X-ray 2.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:12794311, ECO:0000269|PubMed:18561914, ECO:0000269|PubMed:22637475, ECO:0000269|PubMed:29497057}. Endoplasmic reticulum lumen {ECO:0000305|PubMed:29497057}. Sarcoplasmic reticulum lumen {ECO:0000269|PubMed:22637475}. Note=Retained in the endoplasmic reticulum (ER), and sarcoplasmic reticulum (SR) under normal conditions (PubMed:22637475). Up-regulated and secreted by the ER/SR in response to ER stress and hypoxia (PubMed:22637475, PubMed:29497057). {ECO:0000269|PubMed:22637475, ECO:0000269|PubMed:29497057}. |
| Mouse PG classification | NA |
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