| Gene Information | |
|---|---|
| Gene Name | ARNT |
| Organism | Homo sapiens (Human) |
| Gene Length | 789 |
| Protein Names | Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000143437 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P27540 |
| Gene Card | ARNT |
| Uniprot ID | P27540 |
| Pfam | PF00010; PF00989 |
| In ASD | no |
| Allosteric Prediction | yes (0.539601795) |
| Ortholog in Animals | Alpaca_ ARNT ( ortholog_one2one ) Dog_ ARNT ( ortholog_one2one ) GuineaPig_ Arnt ( ortholog_one2one ) Macaque_ ARNT ( ortholog_one2one ) Mouse_ Arnt ( ortholog_one2one ) Pig_ ARNT ( ortholog_one2one ) Rat_ Arnt ( ortholog_one2one ) Rabbit_ ARNT ( ortholog_one2one ) |
| Ohnologs | ARNT2 |
| Paralogs | ARNTL, NPAS2, ARNT2, CLOCK, PASD1, ARNTL2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002714(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 1X0O (NMR - ) 2A24 (NMR - ) 2B02 (X-ray 1.50A ) 2HV1 (NMR - ) 2K7S (NMR - ) 3F1N (X-ray 1.48A ) 3F1O (X-ray 1.60A ) 3F1P (X-ray 1.17A ) 3H7W (X-ray 1.65A ) 3H82 (X-ray 1.50A ) 4EQ1 (X-ray 1.60A ) 4GHI (X-ray 1.50A ) 4GS9 (X-ray 1.72A ) 4H6J (X-ray 1.52A ) 4LPZ (X-ray 3.15A ) 4PKY (X-ray 3.20A ) 4XT2 (X-ray 1.70A ) 5TBM (X-ray 1.85A ) 5UFP (X-ray 1.90A ) 5V0L (X-ray 4.00A ) 6CZW (X-ray 1.60A ) 6D09 (X-ray 1.85A ) 6D0B (X-ray 1.60A ) 6D0C (X-ray 1.50A ) 6X21 (X-ray 1.54A ) 6X28 (X-ray 1.92A ) 6X2H (X-ray 2.00A ) 6X37 (X-ray 1.94A ) 6X3D (X-ray 2.00A ) |
| DBSNP | rs2229175 rs1805133 rs10305741 rs2275237 |
| Subcellular location [CC] | Nucleus {ECO:0000305|PubMed:34521881}. |
| Mouse PG classification | NA |
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