| Gene Information | |
|---|---|
| Gene Name | ARMCX2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 632 |
| Protein Names | Armadillo repeat-containing X-linked protein 2 (ARM protein lost in epithelial cancers on chromosome X 2) (Protein ALEX2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000184867 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q7L311 |
| Gene Card | ARMCX2 |
| Uniprot ID | Q7L311 |
| Pfam | PF04826 |
| In ASD | no |
| Allosteric Prediction | no (-2.024138952) |
| Ortholog in Animals | Alpaca_ ARMCX2 ( ortholog_one2one ) Dog_ ARMCX2 ( ortholog_one2one ) GuineaPig_ ARMCX2 ( ortholog_one2one ) Macaque_ ARMCX2 ( ortholog_one2one ) Mouse_ Armcx2 ( ortholog_one2one ) Pig_ ARMCX2 ( ortholog_one2one ) Rat_ Armcx2 ( ortholog_one2one ) Rabbit_ ARMCX2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ARMC12, GPRASP2, ARMCX4, ARMCX1, ARMCX5, GPRASP1, ARMCX3, ARMC10, ARMCX6, ARMCX5-GPRASP2, BHLHB9 |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not expressed in pancreas and ovarian carcinomas. {ECO:0000269|PubMed:11162520}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion {ECO:0000250|UniProtKB:Q6A058}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8BHS6}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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