| Gene Information | |
|---|---|
| Gene Name | ARMCX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 453 |
| Protein Names | Armadillo repeat-containing X-linked protein 1 (ARM protein lost in epithelial cancers on chromosome X 1) (Protein ALEX1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000126947 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9P291 |
| Gene Card | ARMCX1 |
| Uniprot ID | Q9P291 |
| Pfam | PF04826 |
| In ASD | no |
| Allosteric Prediction | no (-1.146382405) |
| Ortholog in Animals | Alpaca_ ARMCX1 ( ortholog_one2one ) Alpaca_ ARMCX1 ( ortholog_one2many ) Dog_ ARMCX1 ( ortholog_one2one ) GuineaPig_ ARMCX1 ( ortholog_one2one ) Macaque_ ARMCX1 ( ortholog_one2one ) Mouse_ Armcx1 ( ortholog_one2one ) Pig_ ARMCX1 ( ortholog_one2one ) Rat_ Armcx1 ( ortholog_one2one ) Rabbit_ ARMCX1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ARMCX2, ARMC12, GPRASP2, ARMCX4, ARMCX5, GPRASP1, ARMCX3, ARMC10, ARMCX6, ARMCX5-GPRASP2, BHLHB9 |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carcinomas. {ECO:0000269|PubMed:11162520}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion {ECO:0000250|UniProtKB:Q9CX83}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9CX83}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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