| Gene Information | |
|---|---|
| Gene Name | MIEF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 463 |
| Protein Names | Mitochondrial dynamics protein MID51 (Mitochondrial dynamics protein of 51 kDa) (Mitochondrial elongation factor 1) (Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like) (SMCR7-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000100335 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NQG6 |
| Gene Card | MIEF1 |
| Uniprot ID | Q9NQG6 |
| Pfam | PF20266 |
| In ASD | no |
| Allosteric Prediction | no (-1.193453763) |
| Ortholog in Animals | Alpaca_ MIEF1 ( ortholog_one2one ) Dog_ MIEF1 ( ortholog_one2one ) GuineaPig_ MIEF1 ( ortholog_one2one ) Macaque_ MIEF1 ( ortholog_one2one ) Mouse_ Mief1 ( ortholog_one2one ) Rat_ Mief1 ( ortholog_one2one ) Rabbit_ MIEF1 ( ortholog_one2one ) |
| Ohnologs | MIEF2 |
| Paralogs | MIEF2 |
| Tissue | NA |
| Tissue Specificity | Expression is relatively high in heart, skeletal muscle, pancreas and kidney. {ECO:0000269|PubMed:21701560}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4NXT (X-ray 2.12A ) 4NXU (X-ray 2.30A ) 4NXV (X-ray 2.30A ) 4NXW (X-ray 2.55A ) 4NXX (X-ray 2.55A ) 5X9B (X-ray 2.70A ) 5X9C (X-ray 1.85A ) |
| DBSNP | rs2272830 rs17001213 rs2232088 rs2232091 |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000269|PubMed:21508961, ECO:0000269|PubMed:21701560, ECO:0000269|PubMed:24515348}; Single-pass membrane protein {ECO:0000269|PubMed:21508961, ECO:0000269|PubMed:21701560, ECO:0000269|PubMed:24515348}. |
| Mouse PG classification | NA |
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