| Gene Information | |
|---|---|
| Gene Name | ARL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 184 |
| Protein Names | ADP-ribosylation factor-like protein 2 |
| Target Name | adp-ribosylation factor-like protein 2 |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000213465 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P36404 |
| Gene Card | ARL2 |
| Uniprot ID | P36404 |
| Pfam | PF00025 |
| In ASD | no |
| Allosteric Prediction | no (-0.268382537) |
| Ortholog in Animals | Alpaca_ ARL2 ( ortholog_one2one ) Dog_ ARL2 ( ortholog_one2many ) GuineaPig_ ARL2 ( ortholog_one2one ) Macaque_ ARL2 ( ortholog_one2one ) Mouse_ Arl2 ( ortholog_one2one ) Pig_ ARL2 ( ortholog_one2one ) Rat_ Arl2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ARL5C, ARF4, ARL10, ARL16, ARFRP1, ARL17B, ARL17A, ARF3, ARF1, ARL1, ARL8B, TRIM23, ARL4D, ARL9, ARL14, ARL4A, ARL6, ARL13B, ARL13A, ARL15, ARL11, ARL5A, ARF5, ARL3, ARL8A, SAR1B, ARF6, ARL4C, ARL5B, SAR1A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3DOE (X-ray 2.25A ) 3DOF (X-ray 3.30A ) |
| DBSNP | rs664226 |
| Subcellular location [CC] | Mitochondrion intermembrane space {ECO:0000305|PubMed:30945270}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria. The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria (By similarity). Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. {ECO:0000250|UniProtKB:O08697}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |