| Gene Information | |
|---|---|
| Gene Name | RHOBTB3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 611 |
| Protein Names | Rho-related BTB domain-containing protein 3 (EC 3.6.1.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000164292 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O94955 |
| Gene Card | RHOBTB3 |
| Uniprot ID | O94955 |
| Pfam | PF00651; PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-1.061854089) |
| Ortholog in Animals | Alpaca_ RHOBTB3 ( ortholog_one2one ) Dog_ RHOBTB3 ( ortholog_one2one ) GuineaPig_ RHOBTB3 ( ortholog_one2one ) Macaque_ RHOBTB3 ( ortholog_one2one ) Mouse_ Rhobtb3 ( ortholog_one2one ) Pig_ RHOBTB3 ( ortholog_one2one ) Rat_ Rhobtb3 ( ortholog_one2one ) Rabbit_ RHOBTB3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RND1, CDC42, RHOT1, RHOT2, RAC1, RAC3, RHOJ, RHOA, RHOC, RHOB, RHOV, RHOQ, RHOBTB2, RND2, RND3, RHOD, RHOF, RHOG, RHOU, RAC2, RHOBTB1, RHOH |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highly expressed in neural and cardiac tissues, pancreas, placenta and testis. {ECO:0000269|PubMed:12426103}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17855649 rs2302980 rs34899 |
| Subcellular location [CC] | Golgi apparatus {ECO:0000269|PubMed:19490898}. |
| Mouse PG classification | NA |
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