| Gene Information | |
|---|---|
| Gene Name | ARL13B |
| Organism | Homo sapiens (Human) |
| Gene Length | 428 |
| Protein Names | ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000169379 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q3SXY8 |
| Gene Card | ARL13B |
| Uniprot ID | Q3SXY8 |
| Pfam | PF00025 |
| In ASD | no |
| Allosteric Prediction | no (-1.225834876) |
| Ortholog in Animals | Alpaca_ ARL13B ( ortholog_one2one ) Dog_ ARL13B ( ortholog_one2one ) GuineaPig_ ARL13B ( ortholog_one2one ) Macaque_ ARL13B ( ortholog_one2one ) Mouse_ Arl13b ( ortholog_one2one ) Pig_ ARL13B ( ortholog_one2one ) Rat_ Arl13b ( ortholog_one2one ) Rabbit_ ARL13B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ARL5C, ARF4, ARL10, ARL16, ARL2, ARFRP1, ARL17B, ARL17A, ARF3, ARF1, ARL1, ARL8B, TRIM23, ARL4D, ARL9, ARL14, ARL4A, ARL6, ARL13A, ARL15, ARL11, ARL5A, ARF5, ARL3, ARL8A, SAR1B, ARF6, ARL4C, ARL5B, SAR1A |
| Tissue | NA |
| Tissue Specificity | Expressed in the developing brain. {ECO:0000269|PubMed:25138100}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003990(Rat);0.133333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs121912606 rs863225430 rs121912608 rs33944211 |
| Subcellular location [CC] | Cell projection, cilium membrane {ECO:0000269|PubMed:18554500, ECO:0000269|PubMed:24120134}; Lipid-anchor {ECO:0000269|PubMed:18554500, ECO:0000269|PubMed:24120134}. Cell projection, cilium {ECO:0000269|PubMed:25138100}. Note=Associates to the cilium membrane via palmitoylation. Localizes to proximal ciliary membranes, to an inversin-like subciliary membrane compartment, excluding the transition zone. |
| Mouse PG classification | NA |
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