| Gene Information | |
|---|---|
| Gene Name | RPRD1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 326 |
| Protein Names | Regulation of nuclear pre-mRNA domain-containing protein 1B (Cell cycle-related and expression-elevated protein in tumor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000101413 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NQG5 |
| Gene Card | RPRD1B |
| Uniprot ID | Q9NQG5 |
| Pfam | PF04818; PF16566 |
| In ASD | no |
| Allosteric Prediction | no (-0.74081558) |
| Ortholog in Animals | Alpaca_ RPRD1B ( ortholog_one2one ) GuineaPig_ RPRD1B ( ortholog_one2one ) Macaque_ RPRD1B ( ortholog_one2one ) Mouse_ Rprd1b ( ortholog_one2one ) Rat_ Rprd1b ( ortholog_one2one ) Rabbit_ RPRD1B ( ortholog_one2one ) |
| Ohnologs | RPRD1A |
| Paralogs | RPRD1A, RPRD2 |
| Tissue | NA |
| Tissue Specificity | Preferentially expressed in a range of tumor tissues including colon, lung, liver, breast, prostate, stomach, uterine endometrium and cervical cancers with higher levels in tumors than in adjacent non-tumor tissue (at protein level). {ECO:0000269|PubMed:22264791}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002740(Rat);0.047368(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4FLA (X-ray 2.20A ) 4FU3 (X-ray 1.90A ) 4HFG (X-ray 2.00A ) 4NAD (X-ray 2.80A ) 4Q94 (X-ray 1.85A ) 4Q96 (X-ray 1.85A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:22231121, ECO:0000269|PubMed:22264791}. |
| Mouse PG classification | NA |
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