| Gene Information | |
|---|---|
| Gene Name | ARL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 181 |
| Protein Names | ADP-ribosylation factor-like protein 1 |
| Target Name | adp-ribosylation factor-like protein 1 |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000120805 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P40616 |
| Gene Card | ARL1 |
| Uniprot ID | P40616 |
| Pfam | PF00025 |
| In ASD | no |
| Allosteric Prediction | no (-0.218050891) |
| Ortholog in Animals | Alpaca_ ARL1 ( ortholog_one2one ) Dog_ ARL1 ( ortholog_one2one ) GuineaPig_ ARL1 ( ortholog_one2one ) Macaque_ ARL1 ( ortholog_one2one ) Mouse_ Arl1 ( ortholog_one2one ) Pig_ ARL1 ( ortholog_one2one ) Rat_ Arl1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ARL5C, ARF4, ARL10, ARL16, ARL2, ARFRP1, ARL17B, ARL17A, ARF3, ARF1, ARL8B, TRIM23, ARL4D, ARL9, ARL14, ARL4A, ARL6, ARL13B, ARL13A, ARL15, ARL11, ARL5A, ARF5, ARL3, ARL8A, SAR1B, ARF6, ARL4C, ARL5B, SAR1A |
| Tissue | NA |
| Tissue Specificity | Detected in heart, liver, lung and liver (at protein level). Detected in fetal heart, lung, liver and kidney. Detected in adult heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9624189}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002808(Rat);0.026667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1UPT (X-ray 1.70A ) 4DCN (X-ray 3.01A ) 5EE5 (X-ray 2.28A ) 5J5C (X-ray 3.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:11303027}; Peripheral membrane protein {ECO:0000269|PubMed:11303027}; Cytoplasmic side {ECO:0000269|PubMed:11303027}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:21239483, ECO:0000269|PubMed:27373159, ECO:0000269|PubMed:27436755}. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. |
| Mouse PG classification | NA |
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