| Gene Information | |
|---|---|
| Gene Name | RASIP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 963 |
| Protein Names | Ras-interacting protein 1 (Rain) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000105538 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q5U651 |
| Gene Card | RASIP1 |
| Uniprot ID | Q5U651 |
| Pfam | PF01843; PF00788 |
| In ASD | no |
| Allosteric Prediction | no (-0.721406929) |
| Ortholog in Animals | Alpaca_ RASIP1 ( ortholog_one2one ) Dog_ RASIP1 ( ortholog_one2one ) GuineaPig_ RASIP1 ( ortholog_one2one ) Macaque_ RASIP1 ( ortholog_one2one ) Mouse_ Rasip1 ( ortholog_one2one ) Pig_ RASIP1 ( ortholog_one2one ) Rat_ Rasip1 ( ortholog_one2one ) Rabbit_ RASIP1 ( ortholog_one2one ) |
| Ohnologs | RADIL |
| Paralogs | RADIL |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart. Detected at lower levels in placenta and pancreas. {ECO:0000269|PubMed:15031288}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5KHO (X-ray 2.78A ) 5KHQ (X-ray 2.80A ) |
| DBSNP | rs2287922 |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000269|PubMed:15031288}. Golgi apparatus, Golgi stack {ECO:0000269|PubMed:15031288}. Note=Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS. |
| Mouse PG classification | NA |
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