| Gene Information | |
|---|---|
| Gene Name | ARHGEF39 |
| Organism | Homo sapiens (Human) |
| Gene Length | 335 |
| Protein Names | Rho guanine nucleotide exchange factor 39 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000137135 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8N4T4 |
| Gene Card | ARHGEF39 |
| Uniprot ID | Q8N4T4 |
| Pfam | PF00621 |
| In ASD | no |
| Allosteric Prediction | no (-1.526500533) |
| Ortholog in Animals | Alpaca_ ARHGEF39 ( ortholog_one2one ) Dog_ ARHGEF39 ( ortholog_one2one ) GuineaPig_ ARHGEF39 ( ortholog_one2one ) Macaque_ ARHGEF39 ( ortholog_one2one ) Mouse_ Arhgef39 ( ortholog_one2one ) Pig_ ARHGEF39 ( ortholog_one2one ) Rat_ Arhgef39 ( ortholog_one2one ) Rabbit_ ARHGEF39 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ECT2L, FGD5, FARP1, FARP2, FGD6, FGD4, FGD3, FGD2, FRMD7, FGD1 |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in hepatocellular carcinoma (HCC) compared with their non-cancerous counterparts. {ECO:0000269|PubMed:22327280}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs45567235 rs2297879 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:22327280}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |