| Gene Information | |
|---|---|
| Gene Name | RBPJ |
| Organism | Homo sapiens (Human) |
| Gene Length | 500 |
| Protein Names | Recombining binding protein suppressor of hairless (CBF-1) (J kappa-recombination signal-binding protein) (RBP-J kappa) (RBP-J) (RBP-JK) (Renal carcinoma antigen NY-REN-30) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000168214 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q06330 |
| Gene Card | RBPJ |
| Uniprot ID | Q06330 |
| Pfam | PF09270; PF09271; PF20144 |
| In ASD | no |
| Allosteric Prediction | yes (0.020007863) |
| Ortholog in Animals | Alpaca_ RBPJ ( ortholog_one2one ) Dog_ RBPJ ( ortholog_one2one ) GuineaPig_ RBPJ ( ortholog_one2one ) Macaque_ RBPJ ( ortholog_one2one ) Mouse_ Rbpj ( ortholog_one2one ) Pig_ RBPJ ( ortholog_one2one ) Rat_ Rbpj ( ortholog_one2many ) Rabbit_ RBPJ ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RBPJL |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001323(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2F8X (X-ray 3.25A ) 3NBN (X-ray 3.45A ) 3V79 (X-ray 3.85A ) 6PY8 (X-ray 3.75A ) |
| DBSNP | rs387907270 rs387907271 rs1064372 rs1064376 rs1064381 rs1064384 rs1064387 rs1064402 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Note=Mainly nuclear, upon interaction with RITA/C12orf52, translocates to the cytoplasm, down-regulating the Notch signaling pathway. |
| Mouse PG classification | LPG |
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