| Gene Information | |
|---|---|
| Gene Name | ARHGEF15 |
| Organism | Homo sapiens (Human) |
| Gene Length | 841 |
| Protein Names | Rho guanine nucleotide exchange factor 15 (Ephexin-5) (E5) (Vsm-RhoGEF) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000198844 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O94989 |
| Gene Card | ARHGEF15 |
| Uniprot ID | O94989 |
| Pfam | PF00621 |
| In ASD | no |
| Allosteric Prediction | no (-1.000020387) |
| Ortholog in Animals | Alpaca_ ARHGEF15 ( ortholog_one2one ) Dog_ ARHGEF15 ( ortholog_one2one ) GuineaPig_ ARHGEF15 ( ortholog_one2one ) Macaque_ ARHGEF15 ( ortholog_one2one ) Mouse_ Arhgef15 ( ortholog_one2one ) Pig_ ARHGEF15 ( ortholog_one2one ) Rat_ Arhgef15 ( ortholog_one2one ) Rabbit_ ARHGEF15 ( ortholog_one2one ) |
| Ohnologs | ARHGEF5, NGEF, ARHGEF26, ARHGEF16, ARHGEF19 |
| Paralogs | NGEF, ARHGEF19, ARHGEF5, ARHGEF35, ARHGEF16, ARHGEF26 |
| Tissue | NA |
| Tissue Specificity | Expressed in the vascular smooth muscle of coronary artery. {ECO:0000269|PubMed:12775584}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9890841 rs17857129 rs871841 rs587777166 rs3744647 |
| Subcellular location [CC] | Cell projection, dendrite {ECO:0000250}. Note=Expressed exclusively in dendrites of the developing hippocampus. {ECO:0000250}. |
| Mouse PG classification | NA |
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