| Gene Information | |
|---|---|
| Gene Name | ARHGAP7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1528 |
| Protein Names | Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein) (DLC-1) (HP protein) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96QB1 |
| Gene Card | DLC1 |
| Uniprot ID | Q96QB1 |
| Pfam | PF00620; PF07647; PF01852 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DKY (NMR - ) 2GYT (NMR - ) 2KAP (NMR - ) 2LOZ (NMR - ) 3KUQ (X-ray 2.30A ) 5FZT (X-ray 2.10A ) |
| DBSNP | rs34575560 rs3816748 rs11203495 rs11203494 rs3816747 rs34591797 rs1044092 rs532841 rs121908500 rs149295187 rs1044093 rs1044094 |
| Subcellular location [CC] | Cytoplasm. Cell junction, focal adhesion. Membrane; Peripheral membrane protein. Note=Colocalizes with EF1A1 at actin-rich regions in the cell periphery. |
| Mouse PG classification | NA |
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