Gene Information
Gene NameCLEC4G
OrganismHomo sapiens (Human)
Gene Length293
Protein NamesC-type lectin domain family 4 member G (Liver and lymph node sinusoidal endothelial cell C-type lectin) (LSECtin)
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000182566 )
Evolutionary StageMammalia
AlphaFoldDBQ6UXB4
Gene CardCLEC4G
Uniprot IDQ6UXB4
PfamPF00059
In ASDno
Allosteric Predictionno (-0.542328955)
Ortholog in AnimalsAlpaca_ CLEC4G ( ortholog_one2one )
Dog_ CLEC4G ( ortholog_one2one )
GuineaPig_ CLEC4G ( ortholog_one2one )
Macaque_ CLEC4G ( ortholog_one2one )
Mouse_ Clec4g ( ortholog_one2one )
Pig_ CLEC4G ( ortholog_one2one )
Rat_ Clec4g ( ortholog_one2one )
OhnologsNA
ParalogsASGR1, CLEC4C, CLEC4M, CLEC17A, ASGR2, CLEC4A, CLEC4F, CLEC10A, CLEC6A, FCER2, CD209, CLEC4D, CD207, CLEC4E
Tissueliver, lymph.node, adipose.tissue
Tissue SpecificityExpressed exclusively in fetal and adult liver and in lymph nodes. Specifically expressed by endothelial cells lining lymph node and liver sinuses (at protein level). {ECO:0000269|PubMed:14711836}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell membrane;
Single-pass type II membrane protein {ECO:0000269|PubMed:14711836}.
Mouse PG classificationNA
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