| Gene Information | |
|---|---|
| Gene Name | AREL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 823 |
| Protein Names | Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 2.3.2.26) (Apoptosis-resistant HECT-type E3 ubiquitin transferase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000119682 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O15033 |
| Gene Card | AREL1 |
| Uniprot ID | O15033 |
| Pfam | PF00630; PF00632 |
| In ASD | no |
| Allosteric Prediction | no (-0.441330737) |
| Ortholog in Animals | Alpaca_ AREL1 ( ortholog_one2one ) Dog_ AREL1 ( ortholog_one2one ) GuineaPig_ AREL1 ( ortholog_one2one ) Mouse_ Arel1 ( ortholog_one2one ) Pig_ AREL1 ( ortholog_one2one ) Rat_ Arel1 ( ortholog_one2one ) Rabbit_ AREL1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HERC4, NEDD4, HECTD1, NEDD4L, UBE3B, HUWE1, SMURF1, UBR5, HERC2, HECW2, HERC3, WWP1, UBE3A, UBE3C, SMURF2, HACE1, HECTD2, HECTD4, ITCH, HECW1, WWP2, TRIP12, HERC5, HERC6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.133333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6JX5 (X-ray 2.40A ) 6LOH (X-ray 3.21A ) |
| DBSNP | rs371610162 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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