| Gene Information | |
|---|---|
| Gene Name | MMP25 |
| Organism | Homo sapiens (Human) |
| Gene Length | 562 |
| Protein Names | Matrix metalloproteinase-25 (MMP-25) (EC 3.4.24.-) (Leukolysin) (Membrane-type matrix metalloproteinase 6) (MT-MMP 6) (MTMMP6) (Membrane-type-6 matrix metalloproteinase) (MT6-MMP) (MT6MMP) |
| Target Name | matrix metalloproteinase-25 |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000008516 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NPA2 |
| Gene Card | MMP25 |
| Uniprot ID | Q9NPA2 |
| Pfam | PF00045; PF00413; PF01471 |
| In ASD | no |
| Allosteric Prediction | no (-0.036527507) |
| Ortholog in Animals | Alpaca_ MMP25 ( ortholog_one2many ) Dog_ MMP25 ( ortholog_one2one ) GuineaPig_ MMP25 ( ortholog_one2one ) Macaque_ MMP25 ( ortholog_one2one ) Mouse_ Mmp25 ( ortholog_one2one ) Pig_ MMP25 ( ortholog_one2one ) Rat_ Mmp25 ( ortholog_one2one ) |
| Ohnologs | MMP2, MMP11, MMP15, MMP8, MMP7, MMP20, MMP27, MMP13, MMP3, MMP10, MMP1, MMP17 |
| Paralogs | MMP24, MMP16, MMP21, MMP14, MMP2, MMP1, MMP19, MMP23B, MMP10, MMP9, MMP12, MMP15, MMP27, MMP17, MMP28, MMP13, MMP7, MMP20, MMP26, HPX, MMP8, MMP3, MMP11 |
| Tissue | appendix, bone.marrow, spleen, whole.blood |
| Tissue Specificity | Expressed predominantly in leukocytes, lung and spleen. Expressed also in colon carcinoma, astrocytoma and glioblastomas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix. |
| Mouse PG classification | NA |
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