| Gene Information | |
|---|---|
| Gene Name | MNAT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 309 |
| Protein Names | CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Cyclin-G1-interacting protein) (Menage a trois) (RING finger protein 66) (RING finger protein MAT1) (p35) (p36) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000020426 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P51948 |
| Gene Card | MNAT1 |
| Uniprot ID | P51948 |
| Pfam | PF06391; PF17121 |
| In ASD | no |
| Allosteric Prediction | no (-0.137124984) |
| Ortholog in Animals | Alpaca_ MNAT1 ( ortholog_one2one ) Dog_ MNAT1 ( ortholog_one2one ) GuineaPig_ MNAT1 ( ortholog_one2one ) Macaque_ MNAT1 ( ortholog_one2one ) Mouse_ Mnat1 ( ortholog_one2one ) Pig_ MNAT1 ( ortholog_one2one ) Rat_ Mnat1 ( ortholog_one2one ) Rabbit_ MNAT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest levels in colon and testis. Moderate levels are present thymus, prostate, ovary, and small intestine. The lowest levels are found in spleen and leukocytes. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.232470(Mouse);0.599118(Rat);0.266188(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1G25 (NMR - ) 6NMI (EM 3.70A ) 6O9L (EM 7.20A ) 6O9M (EM 4.40A ) 6TUN (X-ray 2.07A ) 6XBZ (EM 2.80A ) 6XD3 (EM 3.30A ) 7B5O (EM 2.50A ) 7B5Q (EM 2.50A ) 7EGB (EM 3.30A ) 7EGC (EM 3.90A ) 7ENA (EM 4.07A ) 7ENC (EM 4.13A ) 7LBM (EM 4.80A ) 7NVR (EM 4.50A ) 7NVW (EM 4.30A ) 7NVX (EM 3.90A ) 7NVY (EM 7.30A ) 7NVZ (EM 7.20A ) 7NW0 (EM 6.60A ) |
| DBSNP | rs35188899 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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