| Gene Information | |
|---|---|
| Gene Name | AQR |
| Organism | Homo sapiens (Human) |
| Gene Length | 1485 |
| Protein Names | RNA helicase aquarius (EC 3.6.4.13) (Intron-binding protein of 160 kDa) (IBP160) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000021776 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60306 |
| Gene Card | AQR |
| Uniprot ID | O60306 |
| Pfam | PF13086; PF13087; PF16399 |
| In ASD | no |
| Allosteric Prediction | no (-0.336860421) |
| Ortholog in Animals | Alpaca_ AQR ( ortholog_one2one ) Dog_ AQR ( ortholog_one2one ) GuineaPig_ AQR ( ortholog_one2one ) Macaque_ AQR ( ortholog_one2one ) Mouse_ Aqr ( ortholog_one2one ) Pig_ AQR ( ortholog_one2one ) Rat_ Aqr ( ortholog_one2one ) Rabbit_ AQR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SETX, UPF1, DNA2, IGHMBP2, HELZ, ZNFX1, MOV10, HELZ2, MOV10L1, CT55 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.028103(Rat);0.152676(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4PJ3 (X-ray 2.30A ) 5MQF (EM 5.90A ) 5XJC (EM 3.60A ) 5YZG (EM 4.10A ) 5Z56 (EM 5.10A ) 5Z57 (EM 6.50A ) 6FF7 (EM 4.50A ) 6ICZ (EM 3.00A ) 6ID0 (EM 2.90A ) 6ID1 (EM 2.86A ) 6QDV (EM 3.30A ) 7A5P (EM 5.00A ) 7ABI (EM 8.00A ) 7W59 (EM 3.60A ) 7W5A (EM 3.60A ) 7W5B (EM 4.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11991638, ECO:0000269|PubMed:25599396, ECO:0000269|PubMed:28076346, ECO:0000269|PubMed:28502770}. Nucleus, nucleoplasm {ECO:0000269|PubMed:16949364}. Note=Localizes to speckle-like regions of the nucleoplasm. {ECO:0000269|PubMed:16949364}. |
| Mouse PG classification | NA |
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