| Gene Information | |
|---|---|
| Gene Name | TULP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 442 |
| Protein Names | Tubby-related protein 3 (Tubby-like protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000078246 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75386 |
| Gene Card | TULP3 |
| Uniprot ID | O75386 |
| Pfam | PF01167; PF16322 |
| In ASD | no |
| Allosteric Prediction | no (-0.678886164) |
| Ortholog in Animals | Alpaca_ TULP3 ( ortholog_one2one ) GuineaPig_ TULP3 ( ortholog_one2one ) Macaque_ TULP3 ( ortholog_one2one ) Mouse_ Tulp3 ( ortholog_one2one ) Pig_ TULP3 ( ortholog_one2one ) Rat_ Tulp3 ( ortholog_one2one ) Rabbit_ TULP3 ( ortholog_one2one ) |
| Ohnologs | TULP2, TULP1, TUB |
| Paralogs | TULP2, WDR35, TUB, TULP1, TULP4 |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels in testis, ovaries, thyroid, and spinal chord. {ECO:0000269|PubMed:9828123}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. Cell membrane. Cell projection, cilium {ECO:0000269|PubMed:27932497}. Cytoplasm {ECO:0000250}. Secreted {ECO:0000250}. Note=Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha. {ECO:0000250}. |
| Mouse PG classification | NA |
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