Gene Information
Gene NameAQPEP
OrganismHomo sapiens (Human)
Gene Length990
Protein NamesAminopeptidase Q (AP-Q) (APQ) (EC 3.4.11.-) (CHL2 antigen) (Laeverin)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ6Q4G3
Gene CardLVRN
Uniprot IDQ6Q4G3
PfamPF11838; PF01433; PF17900
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificitySpecifically expressed in placenta and not in other tissues. Mainly found at the cell surface region of the extravillous trophoblasts. Detected on extravillous trophoblasts in the outer layer of the chorion laeve in the fetal membrane Not detected on either fetal amnionic epithelial cells or maternal decidual cells. Also detected in the migrating extravillous trophoblasts in the maternal decidual tissues (at protein level). {ECO:0000269|PubMed:14706636}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17138632  rs10078759  rs17138681 
Subcellular location [CC]Membrane {ECO:0000303|PubMed:17525158};
Single-pass type II membrane protein {ECO:0000303|PubMed:17525158}.
Mouse PG classificationNA
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