| Gene Information | |
|---|---|
| Gene Name | AQP8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 261 |
| Protein Names | Aquaporin-8 (AQP-8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000103375 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O94778 |
| Gene Card | AQP8 |
| Uniprot ID | O94778 |
| Pfam | PF00230 |
| In ASD | no |
| Allosteric Prediction | no (-0.265875849) |
| Ortholog in Animals | Alpaca_ AQP8 ( ortholog_one2one ) Dog_ AQP8 ( ortholog_one2one ) GuineaPig_ AQP8 ( ortholog_one2one ) Macaque_ AQP8 ( ortholog_one2one ) Mouse_ Aqp8 ( ortholog_one2one ) Pig_ AQP8 ( ortholog_one2one ) Rat_ Aqp8 ( ortholog_one2one ) Rabbit_ AQP8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MIP, AQP3, AQP1, AQP5, AQP4, AQP6, AQP10, AQP7B, AQP7, AQP9, AQP2 |
| Tissue | colon, pancreas |
| Tissue Specificity | Detected in the sperm midpiece (at protein level) (PubMed:28042826). Expressed only in pancreas and colon. {ECO:0000269|PubMed:28042826}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2287798 |
| Subcellular location [CC] | Mitochondrion membrane {ECO:0000305|PubMed:28042826}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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