| Gene Information | |
|---|---|
| Gene Name | IKBIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 350 |
| Protein Names | Inhibitor of nuclear factor kappa-B kinase-interacting protein (I kappa-B kinase-interacting protein) (IKBKB-interacting protein) (IKK-interacting protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000166130 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q70UQ0 |
| Gene Card | IKBIP |
| Uniprot ID | Q70UQ0 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.404354978) |
| Ortholog in Animals | Alpaca_ IKBIP ( ortholog_one2one ) Dog_ IKBIP ( ortholog_one2one ) GuineaPig_ IKBIP ( ortholog_one2one ) Macaque_ IKBIP ( ortholog_one2one ) Mouse_ Ikbip ( ortholog_one2one ) Pig_ IKBIP ( ortholog_one2one ) Rat_ Ikbip ( ortholog_one2one ) Rabbit_ IKBIP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in vein endothelial cells. Isoform 4 is expressed in lung, kidney, spleen, thymus and skeletal muscle. {ECO:0000269|PubMed:15389287}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1048906 rs12322444 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15389287}; Single-pass membrane protein {ECO:0000269|PubMed:15389287}. Note=Isoform 4 deletion of the hydrophobic, or transmembrane region between AA 45-63 results in uniform distribution throughout the cell, suggesting that this region is responsible for endoplasmic reticulum localization. |
| Mouse PG classification | NA |
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