| Gene Information | |
|---|---|
| Gene Name | AQP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 292 |
| Protein Names | Aquaporin-3 (AQP-3) (Aquaglyceroporin-3) |
| Target Name | aquaporin-3 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000165272 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q92482 |
| Gene Card | AQP3 |
| Uniprot ID | Q92482 |
| Pfam | PF00230 |
| In ASD | no |
| Allosteric Prediction | no (-0.255546903) |
| Ortholog in Animals | Alpaca_ AQP3 ( ortholog_one2one ) Dog_ AQP3 ( ortholog_one2one ) GuineaPig_ AQP3 ( ortholog_one2one ) Macaque_ AQP3 ( ortholog_one2one ) Mouse_ Aqp3 ( ortholog_one2one ) Pig_ AQP3 ( ortholog_one2one ) Rat_ Aqp3 ( ortholog_one2one ) Rabbit_ AQP3 ( ortholog_one2one ) |
| Ohnologs | AQP9, AQP10 |
| Paralogs | MIP, AQP1, AQP5, AQP4, AQP6, AQP10, AQP8, AQP7B, AQP7, AQP9, AQP2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34942735 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12239222}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P47862}. Basolateral cell membrane {ECO:0000250|UniProtKB:P47862}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P47862}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |