| Gene Information | |
|---|---|
| Gene Name | PXDNL |
| Organism | Homo sapiens (Human) |
| Gene Length | 1463 |
| Protein Names | Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000147485 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | A1KZ92 |
| Gene Card | PXDNL |
| Uniprot ID | A1KZ92 |
| Pfam | PF03098; PF07679; PF13855; PF00093 |
| In ASD | no |
| Allosteric Prediction | no (-0.883901736) |
| Ortholog in Animals | Alpaca_ PXDNL ( ortholog_one2one ) Dog_ PXDNL ( ortholog_one2one ) Macaque_ PXDNL ( ortholog_one2one ) Rabbit_ PXDNL ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EPX, PXDN, TPO, LPO, MPO |
| Tissue | heart, testis, atrium |
| Tissue Specificity | the 57 kDa isoform PMR1 is the only form detected at protein levels in human cell lines (PubMed:22543864). Expressed in heart (PubMed:24253521). {ECO:0000269|PubMed:22543864, ECO:0000269|PubMed:24253521}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7833909 rs16916235 rs16916207 rs2977020 rs11774588 rs7827446 rs1052704 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:24253521}. Endoplasmic reticulum {ECO:0000269|PubMed:24253521}. Cell membrane {ECO:0000269|PubMed:24253521}.; [Isoform PMR1]: Cytoplasm. Note=Associates with polysomes. |
| Mouse PG classification | NA |
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