Gene Information
Gene NameAPPBP2
OrganismHomo sapiens (Human)
Gene Length585
Protein NamesAmyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2) (Protein interacting with APP tail 1)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000062725 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ92624
Gene CardAPPBP2
Uniprot IDQ92624
PfamNA
In ASDno
Allosteric Predictionno (-0.322567152)
Ortholog in AnimalsAlpaca_ APPBP2 ( ortholog_one2one )
Dog_ APPBP2 ( ortholog_one2one )
GuineaPig_ APPBP2 ( ortholog_one2one )
Macaque_ APPBP2 ( ortholog_one2one )
Mouse_ Appbp2 ( ortholog_one2one )
Pig_ APPBP2 ( ortholog_one2one )
Rat_ Appbp2 ( ortholog_one2one )
Rabbit_ APPBP2 ( ortholog_one2one )
OhnologsNA
ParalogsKLC1, KLC2, KLC3, NPHP3, KLC4
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34146848 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:11742091}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:9843960}. Membrane {ECO:0000269|PubMed:9843960};
Peripheral membrane protein {ECO:0000269|PubMed:9843960}. Note=Associated with membranes and microtubules. {ECO:0000269|PubMed:9843960}.
Mouse PG classificationNA
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