| Gene Information | |
|---|---|
| Gene Name | APIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 242 |
| Protein Names | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) (hAPIP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000149089 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96GX9 |
| Gene Card | APIP |
| Uniprot ID | Q96GX9 |
| Pfam | PF00596 |
| In ASD | no |
| Allosteric Prediction | no (-0.778677769) |
| Ortholog in Animals | Alpaca_ APIP ( ortholog_one2one ) GuineaPig_ APIP ( ortholog_one2one ) Macaque_ APIP ( ortholog_one2one ) Mouse_ Apip ( ortholog_one2one ) Pig_ APIP ( ortholog_one2one ) Rat_ Apip ( ortholog_one2one ) Rabbit_ APIP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is ubiquitously expressed. Isoform 2 is expressed at lower levels and detected in heart, brain, pancreas, liver, placenta, skeletal muscle and kidney. {ECO:0000269|PubMed:15262985, ECO:0000269|PubMed:23285211}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4M6R (X-ray 2.00A ) |
| DBSNP | rs2956114 rs17850326 rs1977420 rs17850327 |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03116, ECO:0000269|PubMed:15262985, ECO:0000269|PubMed:23285211}. |
| Mouse PG classification | NA |
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