| Gene Information | |
|---|---|
| Gene Name | APOBEC3H |
| Organism | Homo sapiens (Human) |
| Gene Length | 200 |
| Protein Names | DNA dC->dU-editing enzyme APOBEC-3H (EC 3.5.4.38) (APOBEC-related protein 10) (ARP-10) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H) (A3H) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000100298 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q6NTF7 |
| Gene Card | APOBEC3H |
| Uniprot ID | Q6NTF7 |
| Pfam | PF18771 |
| In ASD | no |
| Allosteric Prediction | no (-0.07837431) |
| Ortholog in Animals | Alpaca_ APOBEC3H ( ortholog_one2one ) Dog_ APOBEC3Z3 ( ortholog_one2one ) Macaque_ APOBEC3H ( ortholog_one2one ) Mouse_ Apobec3 ( ortholog_one2one ) Rat_ Apobec3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | APOBEC3B, APOBEC3A, APOBEC2, APOBEC3C, APOBEC3F, APOBEC3D, APOBEC3G, AICDA, APOBEC1 |
| Tissue | NA |
| Tissue Specificity | Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung, testis, ovary, fetal liver and skin. {ECO:0000269|PubMed:16571802, ECO:0000269|PubMed:20308164}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5W45 (X-ray 2.49A ) 6B0B (X-ray 3.28A ) 6BBO (X-ray 3.43A ) |
| DBSNP | rs139293 rs139297 rs139298 rs139299 rs139300 rs139302 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Cytoplasm, P-body. Note=Haplotype 1 is distributed in both the nucleus and cytoplasm, whereas haplotype 2 is predominantly cytoplasmic. |
| Mouse PG classification | NA |
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