| Gene Information | |
|---|---|
| Gene Name | APOBEC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 236 |
| Protein Names | C->U-editing enzyme APOBEC-1 (EC 3.5.4.36) (Apolipoprotein B mRNA-editing enzyme 1) (HEPR) (mRNA(cytosine(6666)) deaminase 1) |
| Target Name | c->u-editing enzyme apobec-1 |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000111701 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P41238 |
| Gene Card | APOBEC1 |
| Uniprot ID | P41238 |
| Pfam | PF18774 |
| In ASD | no |
| Allosteric Prediction | yes (0.079402592) |
| Ortholog in Animals | Alpaca_ APOBEC1 ( ortholog_one2one ) Dog_ APOBEC1 ( ortholog_one2one ) GuineaPig_ APOBEC1 ( ortholog_one2one ) Macaque_ APOBEC1 ( ortholog_one2one ) Mouse_ Apobec1 ( ortholog_one2one ) Pig_ APOBEC1 ( ortholog_one2one ) Rat_ Apobec1 ( ortholog_one2one ) Rabbit_ APOBEC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | APOBEC3B, APOBEC3A, APOBEC2, APOBEC3H, APOBEC3C, APOBEC3F, APOBEC3D, APOBEC3G, AICDA |
| Tissue | duodenum, small.intestine |
| Tissue Specificity | Expressed exclusively in the small intestine. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6X91 (X-ray 3.51A ) |
| DBSNP | rs2302515 rs12820011 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:22580899}. |
| Mouse PG classification | NA |
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