| Gene Information | |
|---|---|
| Gene Name | NECAP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 263 |
| Protein Names | Adaptin ear-binding coat-associated protein 2 (NECAP endocytosis-associated protein 2) (NECAP-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000157191 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NVZ3 |
| Gene Card | NECAP2 |
| Uniprot ID | Q9NVZ3 |
| Pfam | PF07933 |
| In ASD | no |
| Allosteric Prediction | no (-0.414242172) |
| Ortholog in Animals | Alpaca_ NECAP2 ( ortholog_one2one ) Dog_ NECAP2 ( ortholog_one2many ) GuineaPig_ NECAP2 ( ortholog_one2one ) Macaque_ NECAP2 ( ortholog_one2one ) Mouse_ Necap2 ( ortholog_one2one ) Pig_ NECAP2 ( ortholog_one2one ) Rat_ Necap2 ( ortholog_one2one ) Rabbit_ NECAP2 ( ortholog_one2one ) |
| Ohnologs | NECAP1 |
| Paralogs | NECAP1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002419(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35056694 |
| Subcellular location [CC] | Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Colocalizes with AP-2 at the plasma membrane. {ECO:0000250}. |
| Mouse PG classification | NA |
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