| Gene Information | |
|---|---|
| Gene Name | APOA4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 396 |
| Protein Names | Apolipoprotein A-IV (Apo-AIV) (ApoA-IV) (Apolipoprotein A4) |
| Target Name | apolipoprotein a-iv |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000110244 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P06727 |
| Gene Card | APOA4 |
| Uniprot ID | P06727 |
| Pfam | PF01442 |
| In ASD | no |
| Allosteric Prediction | yes (0.214086101) |
| Ortholog in Animals | Alpaca_ APOA4 ( ortholog_one2many ) Dog_ APOA4 ( ortholog_one2one ) GuineaPig_ APOA4 ( ortholog_one2one ) Macaque_ APOA4 ( ortholog_one2one ) Mouse_ Apoa4 ( ortholog_one2one ) Pig_ APOA4 ( ortholog_one2one ) Rat_ Apoa4 ( ortholog_one2one ) Rabbit_ APOA4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | APOE, APOA5, APOA1 |
| Tissue | duodenum, small.intestine, small.intestine.Peyers.patch |
| Tissue Specificity | Synthesized primarily in the intestine and secreted in plasma. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3S84 (X-ray 2.40A ) |
| DBSNP | rs12721041 rs5102 rs12721042 rs5104 rs12721043 rs1181852696 rs201861136 rs773492545 rs121909576 rs2238008 rs1042372 rs150264487 rs5108 rs675 rs5110 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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