Gene Information
Gene NameDPH3
OrganismHomo sapiens (Human)
Gene Length82
Protein NamesDiphthamide biosynthesis protein 3 (CSL-type zinc finger-containing protein 2) (DelGEF-interacting protein 1) (DelGIP1)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000154813 )
Evolutionary StageEukaryota
AlphaFoldDBQ96FX2
Gene CardDPH3
Uniprot IDQ96FX2
PfamPF05207
In ASDno
Allosteric Predictionno (-1.333932161)
Ortholog in AnimalsAlpaca_ DPH3 ( ortholog_one2one )
Dog_ DPH3 ( ortholog_one2one )
GuineaPig_ DPH3 ( ortholog_one2one )
Macaque_ DPH3 ( ortholog_one2one )
Mouse_ Dph3 ( ortholog_one2one )
Pig_ DPH3 ( ortholog_one2many )
Rabbit_ DPH3 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed with highest levels in small intestine, spleen, thymus, heart, liver and lung. {ECO:0000269|PubMed:14527407, ECO:0000269|PubMed:14980502}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2JR7  (NMR 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:14980502}. Nucleus {ECO:0000269|PubMed:14980502}.
Mouse PG classificationNA
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