| Gene Information | |
|---|---|
| Gene Name | HEMGN |
| Organism | Homo sapiens (Human) |
| Gene Length | 484 |
| Protein Names | Hemogen (Erythroid differentiation-associated gene protein) (EDAG-1) (Hemopoietic gene protein) (Negative differentiation regulator protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000136929 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9BXL5 |
| Gene Card | HEMGN |
| Uniprot ID | Q9BXL5 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.107516092) |
| Ortholog in Animals | Alpaca_ HEMGN ( ortholog_one2one ) Macaque_ HEMGN ( ortholog_one2one ) Mouse_ Hemgn ( ortholog_one2one ) Rat_ Hemgn ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | bone.marrow, testis |
| Tissue Specificity | Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level). Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. {ECO:0000269|PubMed:11404085, ECO:0000269|PubMed:14648837, ECO:0000269|PubMed:14730214, ECO:0000269|PubMed:15332117, ECO:0000269|PubMed:15920494, ECO:0000269|PubMed:23436708}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:14730214}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |