| Gene Information | |
|---|---|
| Gene Name | APG12L |
| Organism | Homo sapiens (Human) |
| Gene Length | 140 |
| Protein Names | Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O94817 |
| Gene Card | ATG12 |
| Uniprot ID | O94817 |
| Pfam | PF04110 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:9852036}. |
| Pharmacological Animal Models | 0.039269(Chimpanzee);0.028650(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4GDK (X-ray 2.70A ) 4GDL (X-ray 2.88A ) 4NAW (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Preautophagosomal structure membrane {ECO:0000269|PubMed:22342342}; Peripheral membrane protein {ECO:0000269|PubMed:22342342}. Note=TECPR1 recruits the ATG12-ATG5 conjugate to the autolysosomal membrane. |
| Mouse PG classification | NA |
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