Gene Information
Gene NameAPC2
OrganismHomo sapiens (Human)
Gene Length822
Protein NamesAnaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000115266 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9UJX6
Gene CardANAPC2
Uniprot IDQ9UJX6
PfamPF08672; PF00888
In ASDno
Allosteric Predictionno (-0.447704165)
Ortholog in AnimalsAlpaca_ APC2 ( ortholog_one2one )
Dog_ APC2 ( ortholog_one2one )
GuineaPig_ APC2 ( ortholog_one2one )
Macaque_ APC2 ( ortholog_one2one )
Mouse_ Apc2 ( ortholog_one2one )
Pig_ APC2 ( ortholog_one2one )
Rat_ Apc2 ( ortholog_one2one )
OhnologsAPC
ParalogsAPC
Tissuebrain, cerebral.cortex
Tissue SpecificityNA
Pharmacological Animal Models0.193787(Chimpanzee);0.262564(Mouse);0.358919(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4UI9  (EM  3.60A  4YII  (X-ray  1.80A  5A31  (EM  4.30A  5G04  (EM  4.00A  5G05  (EM  3.40A  5KHR  (EM  6.10A  5KHU  (EM  4.80A  5L9T  (EM  6.40A  5L9U  (EM  6.40A  5LCW  (EM  4.00A  6NXK  (X-ray  2.20A  6OB1  (NMR  6Q6G  (EM  3.20A  6Q6H  (EM  3.20A  6TLJ  (EM  3.80A  6TM5  (EM  3.90A  6TNT  (EM  3.78A  7QE7  (EM  2.90A 
DBSNP NA 
Subcellular location [CC]NA
Mouse PG classificationNA
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