| Gene Information | |
|---|---|
| Gene Name | APC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 468 |
| Protein Names | Calcium-binding mitochondrial carrier protein SCaMC-3 (Mitochondrial ATP-Mg/Pi carrier protein 2) (Mitochondrial Ca(2+)-dependent solute carrier protein 2) (Small calcium-binding mitochondrial carrier protein 3) (Solute carrier family 25 member 23) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000115266 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BV35 |
| Gene Card | SLC25A23 |
| Uniprot ID | Q9BV35 |
| Pfam | PF13202; PF13499; PF00153 |
| In ASD | no |
| Allosteric Prediction | no (-0.447704165) |
| Ortholog in Animals | Alpaca_ APC2 ( ortholog_one2one ) Dog_ APC2 ( ortholog_one2one ) GuineaPig_ APC2 ( ortholog_one2one ) Macaque_ APC2 ( ortholog_one2one ) Mouse_ Apc2 ( ortholog_one2one ) Pig_ APC2 ( ortholog_one2one ) Rat_ Apc2 ( ortholog_one2one ) |
| Ohnologs | APC |
| Paralogs | APC |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Present in various cell lines (at protein level). Expressed at low levels in most tissues examined, with highest expression in brain, skeletal muscle and pancreas. {ECO:0000269|PubMed:15054102, ECO:0000269|PubMed:15123600, ECO:0000269|PubMed:15716113}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:15054102, ECO:0000269|PubMed:15123600, ECO:0000269|PubMed:15716113}; Multi-pass membrane protein {ECO:0000269|PubMed:15054102, ECO:0000269|PubMed:15123600, ECO:0000269|PubMed:15716113}. |
| Mouse PG classification | NA |
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