| Gene Information | |
|---|---|
| Gene Name | APBB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 758 |
| Protein Names | Amyloid beta precursor protein binding family B member 2 (Amyloid-beta (A4) precursor protein-binding family B member 2) (Protein Fe65-like 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000163697 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q92870 |
| Gene Card | APBB2 |
| Uniprot ID | Q92870 |
| Pfam | PF00640; PF00397 |
| In ASD | no |
| Allosteric Prediction | no (-0.429176851) |
| Ortholog in Animals | Alpaca_ APBB2 ( ortholog_one2one ) Dog_ APBB2 ( ortholog_one2one ) GuineaPig_ APBB2 ( ortholog_one2one ) Macaque_ APBB2 ( ortholog_one2one ) Mouse_ Apbb2 ( ortholog_one2one ) Pig_ APBB2 ( ortholog_one2one ) Rat_ Apbb2 ( ortholog_one2one ) Rabbit_ APBB2 ( ortholog_one2one ) |
| Ohnologs | APBB3, APBB1 |
| Paralogs | APBB3, APBB1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:8855266}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4861358 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000269|PubMed:14527950}. Golgi apparatus {ECO:0000269|PubMed:14527950}. Early endosome {ECO:0000269|PubMed:14527950}. |
| Mouse PG classification | NA |
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