| Gene Information | |
|---|---|
| Gene Name | APBA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 575 |
| Protein Names | Amyloid-beta A4 precursor protein-binding family A member 3 (Adapter protein X11gamma) (Neuron-specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000011132 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O96018 |
| Gene Card | APBA3 |
| Uniprot ID | O96018 |
| Pfam | PF00595; PF00640 |
| In ASD | no |
| Allosteric Prediction | no (-0.512868144) |
| Ortholog in Animals | Alpaca_ APBA3 ( ortholog_one2one ) Dog_ APBA3 ( ortholog_one2one ) Macaque_ APBA3 ( ortholog_one2one ) Mouse_ Apba3 ( ortholog_one2one ) Pig_ APBA3 ( ortholog_one2one ) Rat_ Apba3 ( ortholog_one2one ) |
| Ohnologs | APBA2, APBA1 |
| Paralogs | SDCBP, APBA1, APBA2, SDCBP2 |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues examined with lower levels in brain and testis. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.002419(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2YT7 (NMR - ) 2YT8 (NMR - ) 5UWS (X-ray 2.40A ) |
| DBSNP | rs35932323 rs3746119 rs8102086 rs1045236 |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000269|PubMed:19726677}. |
| Mouse PG classification | NA |
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