| Gene Information | |
|---|---|
| Gene Name | UQCRFS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 274 |
| Protein Names | Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (UQCRFS1 mitochondrial targeting sequence) (UQCRFS1 MTS) (Ubiquinol-cytochrome c reductase 8 kDa protein)] |
| Target Name | cytochrome b-c1 complex subunit rieske, mitochondrial |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000169021 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | P47985 |
| Gene Card | UQCRFS1 |
| Uniprot ID | P47985 |
| Pfam | PF00355; PF09165; PF02921 |
| In ASD | no |
| Allosteric Prediction | no (-0.244621437) |
| Ortholog in Animals | Alpaca_ UQCRFS1 ( ortholog_one2one ) Alpaca_ UQCRFS1 ( ortholog_one2many ) Dog_ UQCRFS1 ( ortholog_one2one ) GuineaPig_ UQCRFS1 ( ortholog_one2one ) Mouse_ Uqcrfs1 ( ortholog_one2one ) Pig_ UQCRFS1 ( ortholog_one2one ) Rat_ Uqcrfs1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.642506(Rat);0.241348(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XTE (EM 3.40A ) 5XTH (EM 3.90A ) 5XTI (EM 17.40A ) |
| DBSNP | rs8100724 rs1568346416 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000305|PubMed:31883641}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q5ZLR5}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |