| Gene Information | |
|---|---|
| Gene Name | AP4S1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 144 |
| Protein Names | AP-4 complex subunit sigma-1 (AP-4 adaptor complex subunit sigma-1) (Adaptor-related protein complex 4 subunit sigma-1) (Sigma-1 subunit of AP-4) (Sigma-4-adaptin) (Sigma4-adaptin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000100478 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y587 |
| Gene Card | AP4S1 |
| Uniprot ID | Q9Y587 |
| Pfam | PF01217 |
| In ASD | no |
| Allosteric Prediction | no (-0.86705767) |
| Ortholog in Animals | Alpaca_ AP4S1 ( ortholog_one2one ) Dog_ AP4S1 ( ortholog_one2many ) GuineaPig_ AP4S1 ( ortholog_one2one ) Macaque_ AP4S1 ( ortholog_one2one ) Mouse_ Ap4s1 ( ortholog_one2one ) Pig_ AP4S1 ( ortholog_one2one ) Rat_ Ap4s1 ( ortholog_one2one ) Rabbit_ AP4S1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AP1S1, AP1S2, AP1S3, AP3S1, AP2S1, AP3S2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus, trans-Golgi network membrane {ECO:0000305|PubMed:10436028}; Peripheral membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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