| Gene Information | |
|---|---|
| Gene Name | AP3S2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 193 |
| Protein Names | AP-3 complex subunit sigma-2 (AP-3 complex subunit sigma-3B) (Adaptor-related protein complex 3 subunit sigma-2) (Sigma-3B-adaptin) (Sigma3B-adaptin) (Sigma-adaptin 3b) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000157823 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P59780 |
| Gene Card | AP3S2 |
| Uniprot ID | P59780 |
| Pfam | PF01217 |
| In ASD | no |
| Allosteric Prediction | no (-1.491937136) |
| Ortholog in Animals | Alpaca_ AP3S2 ( ortholog_one2one ) Dog_ AP3S2 ( ortholog_one2one ) GuineaPig_ AP3S2 ( ortholog_one2one ) Mouse_ Ap3s2 ( ortholog_one2one ) Pig_ AP3S2 ( ortholog_one2one ) Rat_ Ap3s2 ( ortholog_one2one ) Rabbit_ AP3S2 ( ortholog_one2one ) |
| Ohnologs | AP3S1 |
| Paralogs | AP1S1, AP1S2, AP1S3, AP3S1, AP2S1, AP4S1 |
| Tissue | NA |
| Tissue Specificity | Present in all adult tissues examined. {ECO:0000269|PubMed:9118953}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. {ECO:0000250}. |
| Mouse PG classification | NA |
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