| Gene Information | |
|---|---|
| Gene Name | MDFIC |
| Organism | Homo sapiens (Human) |
| Gene Length | 246 |
| Protein Names | MyoD family inhibitor domain-containing protein (I-mfa domain-containing protein) (hIC) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000135272 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9P1T7 |
| Gene Card | MDFIC |
| Uniprot ID | Q9P1T7 |
| Pfam | PF15316 |
| In ASD | no |
| Allosteric Prediction | no (-0.344043371) |
| Ortholog in Animals | Alpaca_ MDFIC ( ortholog_one2one ) Dog_ MDFIC ( ortholog_one2one ) GuineaPig_ MDFIC ( ortholog_one2one ) Macaque_ MDFIC ( ortholog_one2one ) Mouse_ Mdfic ( ortholog_one2one ) Pig_ MDFIC ( ortholog_one2one ) Rat_ Mdfic ( ortholog_one2one ) Rabbit_ MDFIC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MDFIC2, MDFI |
| Tissue | NA |
| Tissue Specificity | Expressed in lymphoid organs (spleen, thymus, peripheral blood leukocytes) as well as prostate, uterus and small intestine. {ECO:0000269|PubMed:10671520}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Nucleus, nucleolus. Note=Also shows a granular distribution in the cytoplasm.; [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:10671520, ECO:0000269|PubMed:11139147, ECO:0000269|PubMed:12944466, ECO:0000269|PubMed:16260749}. Note=Weak expression in the nucleus. |
| Mouse PG classification | NA |
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