Gene Information
Gene NameAP1S2
OrganismHomo sapiens (Human)
Gene Length157
Protein NamesAP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin)
Target NameNA
Target TypeNA
Gene Age1714 ( ENSG00000182287 )
Evolutionary StageEukaryota
AlphaFoldDBP56377
Gene CardAP1S2
Uniprot IDP56377
PfamPF01217
In ASDno
Allosteric Predictionno (-0.999832327)
Ortholog in AnimalsAlpaca_ AP1S2 ( ortholog_one2one )
Alpaca_ AP1S2 ( ortholog_one2many )
Dog_ AP1S2 ( ortholog_one2one )
GuineaPig_ AP1S2 ( ortholog_one2one )
Macaque_ AP1S2 ( ortholog_one2one )
Mouse_ Ap1s2 ( ortholog_one2one )
Pig_ AP1S2 ( ortholog_one2one )
Rat_ Ap1s2 ( ortholog_one2one )
Rabbit_ AP1S2 ( ortholog_one2one )
OhnologsAP1S1
ParalogsAP4S1, AP3S1, AP2S1, AP3S2, AP1S1, AP1S3
TissueNA
Tissue SpecificityWidely expressed.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Golgi apparatus. Cytoplasmic vesicle membrane;
Peripheral membrane protein;
Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Mouse PG classificationLPG
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