| Gene Information | |
|---|---|
| Gene Name | CHAC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 184 |
| Protein Names | Glutathione-specific gamma-glutamylcyclotransferase 2 (Gamma-GCG 2) (EC 4.3.2.7) (Cation transport regulator-like protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000143942 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8WUX2 |
| Gene Card | CHAC2 |
| Uniprot ID | Q8WUX2 |
| Pfam | PF04752 |
| In ASD | no |
| Allosteric Prediction | no (-1.425971321) |
| Ortholog in Animals | Alpaca_ CHAC2 ( ortholog_one2one ) Dog_ CHAC2 ( ortholog_one2one ) GuineaPig_ CHAC2 ( ortholog_one2one ) Macaque_ CHAC2 ( ortholog_one2one ) Mouse_ Chac2 ( ortholog_one2one ) Pig_ CHAC2 ( ortholog_one2one ) Rat_ Chac2 ( ortholog_one2one ) Rabbit_ CHAC2 ( ortholog_one2one ) |
| Ohnologs | CHAC1 |
| Paralogs | CHAC1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6K95 (X-ray 2.29A ) 6KY0 (X-ray 2.06A ) 6KY1 (X-ray 2.04A ) |
| DBSNP | rs17851583 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:27913623}. |
| Mouse PG classification | NA |
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