Gene Information
Gene NameAOPEP
OrganismHomo sapiens (Human)
Gene Length819
Protein NamesAminopeptidase O (AP-O) (EC 3.4.11.-)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000148120 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ8N6M6
Gene CardAOPEP
Uniprot IDQ8N6M6
PfamPF09127; PF01433
In ASDno
Allosteric Predictionno (-0.334058198)
Ortholog in AnimalsAlpaca_ AOPEP ( ortholog_one2one )
Dog_ AOPEP ( ortholog_one2one )
GuineaPig_ AOPEP ( ortholog_one2one )
Macaque_ AOPEP ( ortholog_one2one )
Mouse_ Aopep ( ortholog_one2one )
Rat_ Aopep ( ortholog_one2one )
Rabbit_ AOPEP ( ortholog_one2one )
OhnologsNA
ParalogsRNPEPL1, NPEPPS, ERAP1, ENPEP, LTA4H, TRHDE, LNPEP, LVRN, ANPEP, RNPEP, ERAP2
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs16911679  rs16911679  rs16911681  rs34557833 
Subcellular location [CC]Nucleus, nucleolus {ECO:0000250|UniProtKB:Q8BXQ6}.;
[Isoform 3]: Cytoplasm {ECO:0000250|UniProtKB:Q8BXQ6}.
Mouse PG classificationNA
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