| Gene Information | |
|---|---|
| Gene Name | ANP32B |
| Organism | Homo sapiens (Human) |
| Gene Length | 251 |
| Protein Names | Acidic leucine-rich nuclear phosphoprotein 32 family member B (Acidic protein rich in leucines) (Putative HLA-DR-associated protein I-2) (PHAPI2) (Silver-stainable protein SSP29) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000136938 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92688 |
| Gene Card | ANP32B |
| Uniprot ID | Q92688 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.661847094) |
| Ortholog in Animals | Alpaca_ ANP32B ( ortholog_one2one ) Dog_ ANP32B ( ortholog_one2one ) GuineaPig_ ANP32B ( ortholog_one2one ) Macaque_ ANP32B ( ortholog_one2one ) Mouse_ Anp32b ( ortholog_one2one ) Pig_ ANP32B ( ortholog_one2one ) Rat_ Anp32b ( ortholog_one2one ) Rabbit_ ANP32B ( ortholog_one2one ) |
| Ohnologs | ANP32D, ANP32A, ANP32E |
| Paralogs | ANP32A, ANP32D, ANP32E |
| Tissue | substantia.nigra |
| Tissue Specificity | Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta. {ECO:0000269|PubMed:9473664}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.018182(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2ELL (NMR - ) 2RR6 (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Nucleus {ECO:0000269|PubMed:17178712, ECO:0000269|PubMed:24823948, ECO:0000269|PubMed:31217244}. Cytoplasm {ECO:0000269|PubMed:17178712}. Note=Accumulates in the nuclei at the S phase. {ECO:0000250}.; [Isoform 2]: Cytoplasm. Note=Lacks a nuclear localization signal. |
| Mouse PG classification | NA |
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