| Gene Information | |
|---|---|
| Gene Name | ANO8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1232 |
| Protein Names | Anoctamin-8 (Transmembrane protein 16H) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000074855 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9HCE9 |
| Gene Card | ANO8 |
| Uniprot ID | Q9HCE9 |
| Pfam | PF04547 |
| In ASD | no |
| Allosteric Prediction | yes (0.088245177) |
| Ortholog in Animals | Alpaca_ ANO8 ( ortholog_one2one ) Dog_ ANO8 ( ortholog_one2one ) GuineaPig_ ANO8 ( ortholog_one2one ) Macaque_ ANO8 ( ortholog_one2one ) Mouse_ Ano8 ( ortholog_one2one ) Pig_ ANO8 ( ortholog_one2one ) Rat_ Ano8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ANO4, PPP1R7, ANO7, ANO5, ANO2, ANO6, ANO1, ANO10, ANO9, ANO3 |
| Tissue | NA |
| Tissue Specificity | Expressed in embryonic stem cells, fetal brain and neural tissues. {ECO:0000269|PubMed:15647853}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:22946059}; Multi-pass membrane protein {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:22946059}. Note=Shows predominantly an intracellular localization with a weak expression in the cell membrane. |
| Mouse PG classification | NA |
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